Mustafa Durgun Selected Research

Carbonic Anhydrases (Carbonic Anhydrase)

8/2023	Novel bis-ureido-substituted sulfaguanidines and sulfisoxazoles as carbonic anhydrase and acetylcholinesterase inhibitors.
8/2023	Synthesis and Characterization of Novel 1,3-Diaryltriazene-Substituted Sulfaguanidine Derivatives as Selective Carbonic Anhydrase Inhibitors: Biological Evaluation, in Silico ADME/T and Molecular Docking Study.
12/2018	Selective inhibition of carbonic anhydrase-IX by sulphonamide derivatives induces pH and reactive oxygen species-mediated apoptosis in cervical cancer HeLa cells.
3/2016	Synthesis of 4-sulfamoylphenyl-benzylamine derivatives with inhibitory activity against human carbonic anhydrase isoforms I, II, IX and XII.
6/2015	Synthesis of Schiff base derivatives of 4-(2-aminoethyl)-benzenesulfonamide with inhibitory activity against carbonic anhydrase isoforms I, II, IX and XII.
1/2005	Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX.

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Mustafa Durgun Research Topics

Disease

15	Neoplasms (Cancer) 02/2024 - 01/2005
5	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2023 - 12/2018
5	Wounds and Injuries (Trauma) 06/2019 - 07/2013
3	Alzheimer Disease (Alzheimer's Disease) 08/2023 - 04/2021
3	Adenocarcinoma 12/2019 - 12/2017
3	Burns 09/2013 - 12/2012
2	Breast Neoplasms (Breast Cancer) 02/2024 - 10/2022
2	Insulin Resistance 01/2023 - 12/2011
2	Hypoxia (Hypoxemia) 03/2022 - 06/2021
2	Diabetes Mellitus 01/2022 - 04/2021
2	Colorectal Neoplasms (Colorectal Cancer) 01/2019 - 01/2018
2	Infections 10/2015 - 09/2013
1	Epilepsy (Aura) 08/2023
1	Glaucoma 08/2023
1	Parkinson Disease (Parkinson's Disease) 08/2023
1	Metabolic Diseases (Metabolic Disease) 01/2022
1	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2020
1	Colonic Neoplasms (Colon Cancer) 12/2019
1	Carcinoma (Carcinomatosis) 12/2019
1	Prostatic Neoplasms (Prostate Cancer) 12/2019
1	Endometrial Neoplasms (Endometrial Cancer) 12/2017
1	Venous Insufficiency 10/2015
1	AIDS-Related Complex (ARC) 06/2015
1	Cicatrix (Scar) 06/2014
1	Essential Tremor (Essential Tremors) 01/2014
1	absence of Vagina 09/2013
1	Fibrosis (Cirrhosis) 07/2013
1	Inflammation (Inflammations) 07/2013
1	Body Weight (Weight, Body) 12/2011

Drug/Important Bio-Agent (IBA)

7	SulfonamidesIBA 02/2024 - 01/2005
7	Carbonic Anhydrase IXIBA 02/2024 - 01/2018
6	Carbonic Anhydrases (Carbonic Anhydrase)IBA 08/2023 - 01/2005
5	EnzymesIBA 08/2023 - 03/2016
3	Protein Isoforms (Isoforms)IBA 02/2024 - 06/2015
3	AcetylcholinesteraseIBA 08/2023 - 04/2021
3	LigandsIBA 01/2023 - 01/2018
3	IsoenzymesIBA 03/2016 - 01/2005
2	Antineoplastic Agents (Antineoplastics)IBA 10/2022 - 09/2018
2	Proteins (Proteins, Gene)FDA Link 03/2022 - 06/2021
2	ButyrylcholinesteraseIBA 01/2022 - 04/2021
2	BoronIBA 01/2019 - 12/2017
1	Matrix Metalloproteinases (MMPs)IBA 02/2024
1	Glucose (Dextrose)FDA LinkGeneric 01/2023
1	LeptinIBA 01/2023
1	ResistinIBA 01/2023
1	Growth InhibitorsIBA 10/2022
1	Cisplatin (Platino)FDA LinkGeneric 10/2022
1	Schiff Bases (Schiff Base)IBA 10/2022
1	GlucosidasesIBA 01/2022
1	2-(N-cyclohexylamino)ethanesulfonic acid (CHES)IBA 01/2022
1	Cholinesterases (Cholinesterase)IBA 01/2022
1	SLC-0111IBA 06/2021
1	Glycoside Hydrolases (Endoglycosidases)IBA 04/2021
1	SulfaguanidineIBA 04/2021
1	AntioxidantsIBA 12/2020
1	Coordination ComplexesIBA 12/2019
1	MetalsIBA 01/2019
1	DNA (Deoxyribonucleic Acid)IBA 01/2019
1	FluorineIBA 01/2019
1	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2018
1	Benzene (Benzole)IBA 09/2018
1	CopperIBA 09/2018
1	BenzenesulfonamidesIBA 09/2018
1	TriazinesIBA 09/2018
1	disalicylaldehyde ethylenediamine (salen)IBA 01/2018
1	FluoridesIBA 12/2017
1	thymoquinoneIBA 09/2013
1	Oxygen (Dioxygen)IBA 07/2013
1	Nicotine FDA Link 07/2013
1	Silver Sulfadiazine (SSD)FDA LinkGeneric 12/2012
1	octenidineIBA 12/2012
1	ActicoatIBA 12/2012
1	Mupirocin (Bactroban)FDA LinkGeneric 12/2012
1	Blood Glucose (Blood Sugar)IBA 12/2011
1	LipidsIBA 12/2011
1	Insulin (Novolin)FDA Link 12/2011
1	Sulfanilamide FDA Link 01/2005
1	Acetazolamide (Diamox)FDA LinkGeneric 01/2005

Therapy/Procedure

3	Sutures (Suture) 10/2015 - 09/2013
2	Therapeutics 12/2019 - 01/2018
1	Tissue Expansion Devices (Tissue Expander) 06/2019
1	Air Bags (Airbags) 01/2019
1	Perforator Flap 06/2015
1	Traction 06/2014
1	Free Tissue Flaps 01/2014
1	Debridement 09/2013
1	Lipectomy (Liposuction) 09/2013
1	Mammaplasty (Breast Reconstruction) 12/2011